Located in downtown Houston, this is the city's finest boutique hotel. Opened as the Sam Houston in 1924, it presents an eclectic mix of old-world charm and modern panache. The 1924 sign with '$2 per night' is even today a part of the hotel's facade. Business travelers can avail themselves of meeting rooms, conference rooms and Internet access. Once you're done with work, catch up on the latest flick from the DVD library. Otherwise, unwind at the sophisticated Sam Bar, which has great drinks and snacks. A meal at Seventeen, the hotel's award-winning restaurant makes for a perfect end to a long day.