The largest and most important Catholic church in the city is widely considered a masterpiece of Spanish Renaissance architecture. Building started in the 16th century and the interior belongs to this period. However, the main facade is 18th-century baroque. The original plans envisaged two bell towers, but only one was completed. That's why locals affectionately refer to their cathedral as La Manquita (Little One Arm). The side chapels are richly adorned with paintings and the choir stalls are a masterful work of art by sculptor Pedro de Mena. Climb up the bell tower to enjoy the spectacular views.