The palace looks out onto the Piazza San Domenico and houses the various departments that make up the Institute of Oriental Studies. Traces of the old building are visible on the first two levels of the façade. Following the earthquake of 1668, the appearance of the building was changed in 1727. The lower floor was preserved, while the upper floor was restructured. The 'Galleria' is notable for its vault decorated with the 'Gigantomachia' and 'Episodes from the Aeneid'. Another floor was added towards the middle of the nineteenth century. To visit the 'Cabinet', you will need to gain authorization from the administration department.